Glutathione

animal · 2026

Glutathione precursors: a new opportunity for dietary interventions in obesity and metabolic health?

Purpose of review Obesity is a major risk factor for the development of metabolic disorders, including insulin resistance, hepatic steatosis and metabolic syndrome.

Study · 2026

Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis

animal · 2026

Gut microbiota-regulated glutathione metabolic rhythms restore obesity-induced colonic inflammatory oscillations

Obesity disrupts circadian inflammatory rhythms, a defining feature of metabolic syndrome. However, the mechanisms connecting microbial and host circadian communication remain unclear.

animal · 2026

Interference with HMGB1 Inhibits Neuronal Ferroptosis Following Spinal Cord Injury through Targeting ACSL4

This study aimed to investigate the regulatory role of High-mobility group box 1 (HMGB1) in neuronal ferroptosis following spinal cord injury (SCI) and its underlying mechanisms.

Study · 2026

Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: Preclinical Efficacy and Safety Profile

Numerous adverse effects caused by oxidative stress are commonly observed in preterm infants. This stress is caused by the oxidative burden resulting mainly from supplemental oxygen and parenteral nutrition (PN), and by their precarious antioxidant defense system.

review · 2026

Glutathione in Our Diet and Its Role in the Body: From Disease Prevention to Anti-Aging

Background/Objectives : Glutathione (GSH) is a fundamental tripeptide essential for maintaining cellular redox homeostasis, detoxification, and immune regulation. While GSH is synthesized endogenously, its levels typically decline with age, potentially increasing susceptibility to oxidative stress-related conditions.