Glutathione
Also known as: GSH
Glutathione is an endogenous tripeptide (gamma-L-glutamyl-L-cysteinyl-glycine) that serves as the principal intracellular antioxidant in mammalian cells. It is not FDA-approved as a drug in the US; parenteral glutathione is used off-label (and in some compounding settings) for oxidative stress, hepatic support, and — controversially — skin lightening. The FDA has warned against injectable glutathione for skin lightening (2019) due to reports of serious adverse events.
Who's worth your money for Glutathione
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 33 scored sellers
$350 · 15000mg
Best value
Lowest $/mg among scored sellers
$194 · 15000mg · 99.3% purity
Most tested
10 independent COAs on file
$79.99 · 1500mg · 98.5% purity
Average price
$0.05/mg
Sellers
58
45-day trend
-26.8%
47 of 58 sellers have a current price· 2 stale hidden· 12 unverified hidden
Top Merit pick
🇺🇸 Peptide Partners99via Disclosed Labs · 1h ago
$0.02/mg -50.4% vs avg$350
15000mg
no purity- 🇺🇸 Glacier Aminos99
✓ verified at source · 1h ago
$0.04/mg -24.6% vs avg$53.19
1500mg
- 🇺🇸 Hydro Research Peptides97
via Disclosed Labs · 1h ago
$0.06/mg +34.8% vs avg$95.00
1500mg
- 🇺🇸 Prime Peptides96
via Disclosed Labs · 1h ago
$0.05/mg +13.5% vs avg$80.00
1500mg
- 🇺🇸 Sunrise Bioresearch95
via Disclosed Labs · 1h ago
$0.01/mg -72.4% vs avg$194
15000mg
- 🇺🇸 Reta One Labs95
✓ verified at source · 23h ago
$0.02/mg -51.8% vs avg$34.00
1500mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 1h ago
$0.04/mg -14.9% vs avg$59.99
1500mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 1h ago
$0.15/mg +226.2% vs avg$91.99
600mg
- 🇺🇸 Forge Performance Co.94
via Disclosed Labs · 1h ago
$0.04/mg -14.9% vs avg$60.00
1500mg
no purityBuy Code MERIT · 10% off - Nova Peptides94
via Disclosed Labs · 1h ago
$0.05/mg +14.5% vs avg$69.99
1300mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Glutathione
CAS
70-18-8
Molecular formula
C10H17N3O6S
Sequence
ECG
Typical dose range
IV: 600–1200 mg per session (1–3x/week); oral: 250–500 mg/day
Half-life
~10–14 minutes (plasma, IV); cellular retention 24–72 hours post-dose
COAs for Glutathione
117 third-party tests across 31 vendors. Each card links to the full report.
For
Glutathione
by Licensed Peptides· batch White
For
Glutathione
by NG Peptide· batch GLUT-07
For
Glutathione
by VoriLabs· batch GTT-2608-C
For
Glutathione
by VoriLabs· batch GTT-2608-B
For
Glutathione
by Novaglo Research· batch 500150081026GL
For
Glutathione
by CertaPeptides· batch CP-2607-GLU1500
For
Glutathione
by Peptide Plugs· batch 189-04-DK
For
Glutathione
by Novaglo Research· batch 50060073026GT
For
Glutathione
by Certified Peptides· batch GLT5-001
For
Glutathione
by Longeva· batch B-2026-Glutathione-1500-002
For
Glutathione
by Reta One Labs· batch GLT150726
For
Glutathione
by VoriLabs· batch GTT-2606-B
For
Glutathione
by NG Peptide· batch GLUT-005
For
Glutathione
by Modern Research Peptides· batch EMHK2548WED
For
Glutathione
by Synthesis Peptides· batch GL15KC
For
Glutathione
by Orbitrex Peptides· batch GL15KC
For
Glutathione
by Ion Peptide· batch GTT1500-06242026
For
Glutathione
by Ion Peptide· batch GTT1500-06242026
For
Glutathione
by Verified Peptides· batch GL0726041500C
For
Glutathione
by Nova Peptides· batch NV-P-MHC1
For
Glutathione
by Voltera Sciences· batch GT1500-05042026
For
Glutathione
by Voltera Sciences· batch GT1500-05042026
For
GLUTATHIONE
by Verified Peptides· batch GL0526031500B
For
GLUTATHIONE
by Verified Peptides· batch GL052603150OB
20 citations indexed for Glutathione
review
AA-Induced Lipid Peroxidation at the Center of Tumor Cell Apoptosis and Ferroptosis
Polyunsaturated fatty acids (PUFAs), especially gamma-linolenic acid (GLA), arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), can block HMG-CoA reductase activity and thus decrease cholesterol synthesis/formation.
animal · 2026
Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway
Objective This study aimed to examine the potential neuroprotective effects of SXZ on cognitive impairment in naturally aging rats and to explore the underlying molecular mechanisms. Methods Eighteen-month-old Sprague-Dawley rats were used as a natural aging model and administered Shenxian Zhou (SXZ) for 6 months.
Study · 2026
Thiol-Disulfide Homeostasis and Erythrocyte Glutathione Balance in ST-Elevation Myocardial Infarction: A Prospective Case-Control Study
Background : ST-elevation myocardial infarction (STEMI) provokes intense oxidative stress. Serum thiol-disulfide and intracellular glutathione balances reflect oxidative status in different compartments and are rarely measured together.
Study · 2026
Glutaredoxins Rapidly Reduce Glutathione Hydroper- and Polysulfides
Hydropersulfides have gained attention as excellent biochemical nucleophiles and membrane-protective radical scavengers. They form perthiyl radicals, which terminate radical chain reactions through self-recombination, yielding polysulfides. It is currently unknown exactly how polysulfides are subsequently reduced.
review · 2026
Glutathione Biology in Neurodegenerative and Metabolic Diseases: Molecular Mechanisms, Pathophysiological Roles, and Therapeutic Perspectives
Glutathione is an abundant intracellular low-molecular-weight thiol that contributes importantly to cellular redox homeostasis.
Study · 2026
Changes in Glutathione and Homocysteine Concentrations in Treatment-Resistant Depression After Electroconvulsive Therapy
BACKGROUND Electroconvulsive therapy (ECT) is one of the most effective treatment for drug-resistant depression, but the search for reliable biological predictors of its efficacy remains in-conclusive.