For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Immune Modulator

Glutathione

Also known as: GSH

Glutathione is an endogenous tripeptide (gamma-L-glutamyl-L-cysteinyl-glycine) that serves as the principal intracellular antioxidant in mammalian cells. It is not FDA-approved as a drug in the US; parenteral glutathione is used off-label (and in some compounding settings) for oxidative stress, hepatic support, and — controversially — skin lightening. The FDA has warned against injectable glutathione for skin lightening (2019) due to reports of serious adverse events.

Where to buy · live market data

Who's worth your money for Glutathione

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

Highest Merit Score (99) of 33 scored sellers

$0.02/mg

$350 · 15000mg

no COAs yet

Best value

Lowest $/mg among scored sellers

$0.01/mg

$194 · 15000mg · 99.3% purity

Most tested

10 independent COAs on file

$0.05/mg

$79.99 · 1500mg · 98.5% purity

Average price

$0.05/mg

Sellers

58

45-day trend

-26.8%

47 of 58 sellers have a current price· 2 stale hidden· 12 unverified hidden

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

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Compound reference

About Glutathione

CAS

70-18-8

Molecular formula

C10H17N3O6S

Sequence

ECG

Typical dose range

IV: 600–1200 mg per session (1–3x/week); oral: 250–500 mg/day

Half-life

~10–14 minutes (plasma, IV); cellular retention 24–72 hours post-dose

Independent evidence

COAs for Glutathione

117 third-party tests across 31 vendors. Each card links to the full report.

All 117 COAs for Glutathione →
Measured purity 98.3%–100.0% across 86 COAs
Measured purity over time
✓ Vendor-published
99.80 %
Sep 2026
Vanguard Laboratory Strong

For

Glutathione

by Licensed Peptides· batch White

COA on file
Aggregated · 3rd-party listing
99.34 %
Sep 2026
ILS Labs Strong

For

Glutathione

by NG Peptide· batch GLUT-07

Aggregated · 3rd-party listing
99.97 %
Aug 2026
Freedom Diagnostics Moderate

For

Glutathione

by VoriLabs· batch GTT-2608-C

Aggregated · 3rd-party listing
99.96 %
Aug 2026
Freedom Diagnostics Moderate

For

Glutathione

by VoriLabs· batch GTT-2608-B

Aggregated · 3rd-party listing
99.82 %
Aug 2026
Freedom Diagnostics Moderate

For

Glutathione

by Novaglo Research· batch 500150081026GL

Aggregated · 3rd-party listing
98.76 %
Aug 2026
Janoshik Analytical Limited

For

Glutathione

by CertaPeptides· batch CP-2607-GLU1500

Aggregated · 3rd-party listing
99.93 %
Aug 2026
Freedom Diagnostics Moderate

For

Glutathione

by Peptide Plugs· batch 189-04-DK

Aggregated · 3rd-party listing
99.66 %
Aug 2026
Freedom Diagnostics Moderate

For

Glutathione

by Novaglo Research· batch 50060073026GT

Aggregated · 3rd-party listing
99.45 %
Aug 2026
ILS Labs Strong

For

Glutathione

by Certified Peptides· batch GLT5-001

Aggregated · 3rd-party listing
99.98 %
Jul 2026
MZ Biolabs Moderate

For

Glutathione

by Longeva· batch B-2026-Glutathione-1500-002

✓ Vendor-published
99.86 %
Jul 2026
Kovera Labs

For

Glutathione

by Reta One Labs· batch GLT150726

COA on file
Aggregated · 3rd-party listing
99.70 %
Jul 2026
BTLabs Moderate

For

Glutathione

by VoriLabs· batch GTT-2606-B

Aggregated · 3rd-party listing
99.17 %
Jul 2026
ILS Labs Strong

For

Glutathione

by NG Peptide· batch GLUT-005

Aggregated · 3rd-party listing
99.55 %
Jul 2026
Freedom Diagnostics Moderate

For

Glutathione

by Modern Research Peptides· batch EMHK2548WED

Aggregated · 3rd-party listing
99.74 %
Jun 2026
AccumarkLabs Limited

For

Glutathione

by Synthesis Peptides· batch GL15KC

Aggregated · 3rd-party listing
99.74 %
Jun 2026
Freedom Diagnostics Moderate

For

Glutathione

by Orbitrex Peptides· batch GL15KC

✓ Vendor-published
99.81 %
Jun 2026
Freedom Diagnostics Moderate

For

Glutathione

by Ion Peptide· batch GTT1500-06242026

COA on file
Aggregated · 3rd-party listing
99.81 %
Jun 2026
Freedom Diagnostics Moderate

For

Glutathione

by Ion Peptide· batch GTT1500-06242026

Aggregated · 3rd-party listing
98.52 %
Jun 2026
Janoshik Analytical Limited

For

Glutathione

by Verified Peptides· batch GL0726041500C

Aggregated · 3rd-party listing
99.00 %
Jun 2026
Ethos Analytics Strong

For

Glutathione

by Nova Peptides· batch NV-P-MHC1

Aggregated · 3rd-party listing
99.34 %
Jun 2026
ILS Labs Strong

For

Glutathione

by Voltera Sciences· batch GT1500-05042026

Aggregated · 3rd-party listing
99.34 %
Jun 2026
ILS Labs Strong

For

Glutathione

by Voltera Sciences· batch GT1500-05042026

Aggregated · 3rd-party listing
99.01 %
Jun 2026
Janoshik Analytical Limited

For

GLUTATHIONE

by Verified Peptides· batch GL0526031500B

✓ Vendor-published
99.01 %
Jun 2026
Janoshik Analytical Limited

For

GLUTATHIONE

by Verified Peptides· batch GL052603150OB

COA on file
Research depth

20 citations indexed for Glutathione

All research on Glutathione →

review

AA-Induced Lipid Peroxidation at the Center of Tumor Cell Apoptosis and Ferroptosis

Polyunsaturated fatty acids (PUFAs), especially gamma-linolenic acid (GLA), arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), can block HMG-CoA reductase activity and thus decrease cholesterol synthesis/formation.

animal · 2026

Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway

Objective This study aimed to examine the potential neuroprotective effects of SXZ on cognitive impairment in naturally aging rats and to explore the underlying molecular mechanisms. Methods Eighteen-month-old Sprague-Dawley rats were used as a natural aging model and administered Shenxian Zhou (SXZ) for 6 months.

Study · 2026

Thiol-Disulfide Homeostasis and Erythrocyte Glutathione Balance in ST-Elevation Myocardial Infarction: A Prospective Case-Control Study

Background : ST-elevation myocardial infarction (STEMI) provokes intense oxidative stress. Serum thiol-disulfide and intracellular glutathione balances reflect oxidative status in different compartments and are rarely measured together.

Study · 2026

Glutaredoxins Rapidly Reduce Glutathione Hydroper- and Polysulfides

Hydropersulfides have gained attention as excellent biochemical nucleophiles and membrane-protective radical scavengers. They form perthiyl radicals, which terminate radical chain reactions through self-recombination, yielding polysulfides. It is currently unknown exactly how polysulfides are subsequently reduced.

review · 2026

Glutathione Biology in Neurodegenerative and Metabolic Diseases: Molecular Mechanisms, Pathophysiological Roles, and Therapeutic Perspectives

Glutathione is an abundant intracellular low-molecular-weight thiol that contributes importantly to cellular redox homeostasis.

Study · 2026

Changes in Glutathione and Homocysteine Concentrations in Treatment-Resistant Depression After Electroconvulsive Therapy

BACKGROUND Electroconvulsive therapy (ECT) is one of the most effective treatment for drug-resistant depression, but the search for reliable biological predictors of its efficacy remains in-conclusive.