hCG
Also known as: Human Chorionic Gonadotropin, Chorionic Gonadotropin, Pregnyl, Novarel, Ovidrel
Human chorionic gonadotropin is a placental glycoprotein hormone composed of a 92-amino-acid alpha subunit (shared with LH, FSH, and TSH) and a distinct 145-amino-acid beta subunit, joined non-covalently and heavily glycosylated. It acts as an agonist at the luteinizing hormone/choriogonadotropin receptor (LHCGR), mimicking the LH surge. In females it sustains the corpus luteum and progesterone production in early pregnancy and triggers final oocyte maturation and ovulation; in males it stimulates testicular Leydig cells to produce intratesticular testosterone, supporting spermatogenesis. hCG is FDA-approved (e.g., Pregnyl, Novarel, recombinant Ovidrel) for ovulation induction, assisted reproduction, and male hypogonadism/cryptorchidism.
Who's worth your money for hCG
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Average price
—/mg
Sellers
22
45-day trend
building…
0 of 22 sellers have a current price
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About hCG
CAS
9002-61-3
Molecular formula
—
Typical dose range
Fertility (final oocyte maturation): single 5,000-10,000 IU intramuscular or subcutaneous. Male TRT adjunct: commonly 250-500 IU subcutaneous 2-3x weekly (protocols vary, up to ~1,500 IU)
Half-life
~24-36 hours terminal half-life after IM/SC injection (biphasic; longer than LH due to glycosylation)
Common research uses
Safety notes
FDA-approved prescription drug; prescription-only in the US. Risks include ovarian hyperstimulation syndrome (OHSS) in women, thromboembolism, gynecomastia and fluid retention in men, and injection-site reactions. hCG is prohibited in men at all times under the WADA Code (S2 peptide hormones); homeopathic/weight-loss hCG products are not FDA-approved and are considered illegal/fraudulent.
Reconstitution
Lyophilized urinary hCG is reconstituted with the supplied bacteriostatic diluent; refrigerate after reconstitution and use within the labeled window. Recombinant hCG (Ovidrel) is supplied prefilled.
COAs for hCG
25 third-party tests across 9 vendors. Each card links to the full report.
For
HCG
by Genetic Peptide· batch F20350627
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For
HCG
by Certified Peptides· batch 260417HC50003
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For
HCG
by Peptidegurus· batch 24th Feb 2026
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For
hCG
by Moglabs· batch HCG002
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For
hCG
by Arcane Peptides· batch HCG002
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For
hCG 5000 IU
by Arcane Peptides· batch HCG002
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For
hCG 5000 IU
by Moglabs· batch HCG002
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For
HCG
by Bulk Peptides· batch HCG002
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For
HCG
by Moglabs· batch HCG002
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For
HCG
by Arcane Peptides· batch HCG002
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For
HCG
by Kimera Chems· batch KC-HCG-WHT1
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For
hCG 10000 IU
by Ruo Bio· batch RUOJZSC64Z76
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For
HCG
by Certified Peptides· batch HCG05425
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For
HCG 5000 iu
by Kimera Chems· batch Blue Cap
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For
HCG
by Certified Peptides· batch HCG05425
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For
HCG
by Kimera Chems· batch KC-HCG-RED2
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For
HCG
by Kimera Chems· batch Blue Cap
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For
HCG
by Forge Performance Co.· batch Orange Cap
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For
HCG
by Arcane Peptides
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For
HCG
by Ruo Bio
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For
HCG
by Moglabs
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For
HCG
by Nova Peptides· batch NV-P-XJ18
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For
HCG
by Nova Peptides· batch NV-P-XJ18
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For
HCG
by Nova Peptides· batch NV-P-IWQN
20 citations indexed for hCG
Study · 2026
Reference ranges for early pregnancy hCG following embryo transfer: A cohort study of 4807 embryo transfer cycles leading to live birth at term
Objective To establish gestational day-specific reference values for serum hCG in early pregnancy following embryo transfer and identify maternal and treatment-related factors contributing to its variability. Design Retrospective, single-center cohort study.
Study · 2026
Relationship Between Dominant Follicle Diameter on the hCG Trigger Day and Live Birth After Modified Natural Cycle Frozen Embryo Transfer: A Retrospective Cohort Study
Background The impact of dominant follicular diameter at hCG trigger on live birth rate (LBR) in modified natural cycle frozen-thawed embryo transfer (mNC-FET) remains unclear. This study aimed to evaluate this relationship and explore whether flexible triggering based on follicle size is acceptable.
Study · 2026
Nonlinear relationship between serum LH levels on hCG trigger day and live birth rates in patients with fresh embryo transfer: a retrospective cohort study
Background In assisted reproductive technology (ART), the assessment of sex hormones is indispensable. Maintaining an appropriate level of luteinizing hormone (LH) is crucial for ovarian and endometrial development.
Study · 2026
Evaluation and performance of the β-hCG discriminatory zone and targeted ultrasound findings for early pregnancy diagnosis in a high-risk population: a retrospective cohort study at a US safety-net hospital
Study · 2026
Serum Beta-Human Chorionic Gonadotropin (β-hCG) Trends and Their Association With Abdominal Wound Healing After Cesarean Section: An Observational Study
Background and objective Beta-human chorionic gonadotropin (β-hCG) is an established biomarker in pregnancy assessment and in the management of trophoblastic and germ cell disorders.
Study · 2026
Optimization of Pregnancy Testing in the Emergency Department: A Quality Improvement Initiative
Background At our institution, a review of emergency department pregnancy testing identified excess use of serum quantitative (quant) human chorionic gonadotropin (hCG) when only a binary result was clinically indicated. Additionally, we observed delays in point-of-care (POCT) urine hCG turnaround time.