Hexarelin
Also known as: Examorelin
Hexarelin (His-D-2MeTrp-Ala-Trp-D-Phe-Lys-NH2) is a synthetic hexapeptide growth hormone secretagogue developed by Mediolanum (Italy) in the 1990s. It is a potent ghrelin-receptor (GHSR-1a) agonist that also binds the CD36 scavenger receptor, giving it a cardioprotective signal distinct from other GHRPs. It is not FDA-approved for any indication and remains a research-only compound; its clinical development for GH deficiency and cardiac indications did not reach approval. A defining feature versus other GHRPs is rapid, pronounced tachyphylaxis with chronic daily dosing.
Pricing for Hexarelin
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
COAs for Hexarelin
7 third-party tests across 3 vendors. Each card links to the full report.
For
Hexarelin
by Real Peptides
For
Hexarelin
by MedGe Peptides· batch HEX5LT12
For
Hexarelin
by MedGe Peptides· batch HEXSLT12
For
Hexarelin
by Skye Peptides· batch HEX25-5-001
For
Hexarelin
by Peptide Tech· batch 102-HN
Purity not on file
For
Hexarelin
by Real Peptides
Purity not on file
For
Hexarelin
by Skye Peptides· batch HEX25-5-001
13 citations indexed for Hexarelin
animal · 2026
Hexarelin promotes the survival of retinal ganglion cells after optic nerve transection
Objective Hexarelin is a growth hormone secretagogue receptor type 1a agonist with a potent anti-apoptotic effect. We studied the neuroprotective effect of hexarelin on the survival of retinal ganglion cells (RGCs) in the retina following optic nerve transection (ONT).
review · 2026
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Therapeutic peptides are short chains of amino acids used to treat metabolic and endocrine conditions such as obesity and type 2 diabetes.
Study · 2025
Identification of alexamorelin consumption biomarkers using human hepatocyte incubations and high-resolution mass spectrometry
Alexamorelin is a synthetic peptide and growth hormone secretagogue (GHS) with potential performance-enhancing properties, making its use and abuse a topic of interest in clinical research and doping monitoring.
review · 2025
Cisplatin-Induced Muscle Wasting and Atrophy: Molecular Mechanism and Potential Therapeutic Interventions
Platinum-based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects. However, a significant side effect of cisplatin is muscle atrophy, which severely impairs physical strength, diminishes quality of life and complicates cancer therapy.
animal · 2025
Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice
Ghrelin, the endogenous ligand of the growth hormone secretagogue receptor (GHSR), promotes food intake and other feeding behaviors, and stimulates growth hormone (GH) release from the pituitary.
Study · 2024
Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator
The scientific and medical community faced an unprecedented global health hazard that led to nearly 7 million deaths attributable to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.