IGF-1 LR3
Also known as: Long R3 IGF-1
IGF-1 LR3 is an 83-amino-acid modified IGF-1 analog with a 13-residue N-terminal extension (MFPAMPLSSLFVN) and an Arg-3 substitution. These modifications reduce binding to IGF binding proteins (IGFBPs), extending effective half-life and increasing tissue bioavailability relative to native IGF-1. It is a research/cell-culture reagent and is NOT FDA-approved for any human use. Do not confuse with mecasermin (Increlex), which is recombinant human IGF-1 and IS FDA-approved for severe primary IGF-1 deficiency.
Who's worth your money for IGF-1 LR3
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 22 scored sellers
$64.99 · 1mg
Best value
Lowest $/mg among scored sellers
— · 1mg · 99.3% purity
Most tested
7 independent COAs on file
$65.00 · 1mg · 99.8% purity
Average price
$99.04/mg
Sellers
63
45-day trend
+16.2%
48 of 63 sellers have a current price· 24 stale hidden· 2 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · just now
$64.99/mg -34.4% vs avg$64.99
1mg
no purityBuy code MERIT · 10% off- 🇺🇸 Moglabs96
✓ verified at source · just now
$72.00/mg -27.3% vs avg$72.00
1mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · just now
$124.99/mg +26.2% vs avg$125
1mg
no purityBuy code MERIT · 5% off - 🇺🇸 Peptide Crafters94
✓ verified at source · just now
$59.50/mg -39.9% vs avg$59.50
1mg
- Nova Peptides94
✓ verified at source · just now
$79.99/mg -19.2% vs avg$79.99
1mg
- 🇺🇸 Riptide Wellness92
✓ verified at source · just now
$76.76/mg -22.5% vs avg$76.76
1mg
no purity - 🇺🇸 Polaris Peptides90
✓ verified at source · just now
$85.00/mg -14.2% vs avg$85.00
1mg
no purity - 🇺🇸 Peptide Plugs89
✓ verified at source · just now
$70.00/mg -29.3% vs avg$70.00
1mg
- 🇺🇸 Peptidology89
✓ verified at source · just now
$77.40/mg -21.8% vs avg$77.40
1mg
- 🇺🇸 Soma Peptides89
✓ verified at source · just now
$93.00/mg -6.1% vs avg$93.00
1mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About IGF-1 LR3
CAS
143045-27-6
Molecular formula
C400H619N111O115S9
Sequence
MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Typical dose range
20-100 mcg/day subcutaneous or intramuscular injection (research use; commonly 20-50 mcg/day in published protocols)
Half-life
~20-30 hours
COAs for IGF-1 LR3
67 third-party tests across 24 vendors. Each card links to the full report.
For
IGF-1 LR3
by Voltera Sciences· batch IGF1-07082026
For
IGF-1 LR3
by Peptide Plugs· batch 140-01-DK
For
IGF-1 LR3
by Nova Peptides· batch NV-P-ZE8J
For
IGF-1 LR3
by Ion Peptide· batch IGF1-05042026
For
IGF-1 LR3
by Ion Peptide· batch IGF1-052026
For
IGF-1 LR3
by Ion Peptide· batch IGF1-052026
For
IGF-1 LR3
by Peptide Supply Co.· batch IG105192026
For
IGF-1 LR3
by Amino Club· batch IGF0001
For
IGF-1 LR3
by Nova Peptides· batch NV-P-XRXV
For
IGF-1 LR3
by Ion Peptide· batch IGF1-03102026
For
IGF-1 LR3
by Peptide Supply Co.· batch GLR31031026
For
IGF-1 LR3
by Real Peptides
For
IGF-1 LR3
by Nova Peptides· batch NV-P-0FU2
For
IGF-1 LR3
by Mile High Compounds· batch IGF-001-MH-02
For
IGF-1 LR3
by Mile High Compounds· batch IGF-001-MH-02
For
IGF-1 LR3
by Peptide Crafters· batch PC-J2-IGF1
For
IGF-LR3
by Ion Peptide· batch IGFL-010226
For
IGF-1 LR3
by Skye Peptides· batch IGF25-1-003
For
IGF-1 LR3
by Orbitrex Peptides
For
IGF-LR3
by Simple Peptide· batch IGFR12172025-J
For
IGF-1 LR3
by Ion Peptide· batch IL1-1025
For
IGF-1 LR3
by ZLZ peptides· batch cmojgromn00539grxzzwqeri4
For
IGF-1 LR3
by Ion Peptide· batch IL-L-1025
For
IGF-1 LR3
by Cernum Biosciences
12 citations indexed for IGF-1 LR3
Study · 2026
IGF-1 Increases Collagen Deposition by Dermal Fibroblasts: Applications for Tissue Engineering
Tissue engineering using the self-assembly approach represents a promising technology. However, age-related reductions in extracellular matrix deposition by stromal cells limit the mechanical robustness of reconstructed tissues what can be critical for midurethral sling reconstruction.
review · 2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Performance-enhancing drugs (PEDs) marketed as "research compounds" include unregulated peptides intended to modulate the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis.
Study · 2026
Intact Proteoform Analysis by Capillary Electrophoresis-Mass Spectrometry. Are We There Yet?
Mass spectrometry (MS)-based top-down proteomics (TDP) has emerged as a powerful tool for characterizing proteoforms to advance both fundamental and translational research. TDP requires high-efficiency liquid-phase separation, high-resolution MS, and tandem MS.
review · 2026
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Therapeutic peptides are short chains of amino acids used to treat metabolic and endocrine conditions such as obesity and type 2 diabetes.
animal · 2025
Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration
Peripheral nerve injuries lead to significant functional deficits, with no treatment achieving complete recovery. Autologous nerve grafting remains the gold standard, but it is limited by donor site morbidity. Artificial nerve conduits have been developed but have not matched the outcomes of autologous grafts.
animal · 2025
IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep
Insulin-like growth factor-1 (IGF-1) and insulin are important fetal anabolic hormones.