KPV
Also known as: Lysine-Proline-Valine (alpha-MSH 11-13)
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH), corresponding to residues 11-13. It is the smallest alpha-MSH fragment shown to retain anti-inflammatory activity. Research-only; not FDA-approved; evidence is primarily preclinical.
Who's worth your money for KPV
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 40 scored sellers
$320 · 100mg · 99.4% purity
Best value
Lowest $/mg among scored sellers
$250 · 300mg · 99.4% purity
Most tested
17 independent COAs on file
$55.00 · 10mg · 98.5% purity
Average price
$5.32/mg
Sellers
74
45-day trend
-14.8%
61 of 74 sellers have a current price· 3 stale hidden· 18 unverified hidden
Top Merit pick
🇺🇸 Peptide Partners99via Disclosed Labs · 1h ago
$3.20/mg -39.9% vs avg$320
100mg
- 🇺🇸 Glacier Aminos99
✓ verified at source · 1h ago
$3.64/mg -31.6% vs avg$36.39
10mg
- 🇺🇸 Moglabs98
via Disclosed Labs · 1h ago
$6.00/mg +12.7% vs avg$30.00
5mg
- 🇺🇸 Hydro Research Peptides97
via Disclosed Labs · 1h ago
$5.50/mg +3.3% vs avg$55.00
10mg
- 🇺🇸 BioLongevity Labs96
via Disclosed Labs · 1h ago
$10.00/mg +87.8% vs avg$99.97
10mg
- 🇺🇸 Sunrise Bioresearch95
via Disclosed Labs · 1h ago
$0.83/mg -84.3% vs avg$250
300mg
- 🇺🇸 Reta One Labs95
via Disclosed Labs · 1h ago
$3.20/mg -39.9% vs avg$32.00
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 1h ago
$5.00/mg -6.1% vs avg$50.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 1h ago
$7.70/mg +44.7% vs avg$76.99
10mg
- 🇺🇸 Peptide Crafters94
✓ verified at source · 1h ago
$4.00/mg -24.8% vs avg$40.00
10mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
Watch KPV
Get one email when the market actually moves — no newsletter, no noise.
About KPV
CAS
67727-97-3
Molecular formula
C16H30N4O4
Sequence
KPV
Typical dose range
250–500 mcg/day subcutaneous (research use)
Half-life
~4–6 hours (rodent pharmacokinetic data; human data lacking)
COAs for KPV
176 third-party tests across 42 vendors. Each card links to the full report.
For
KPV
by Peptide Plugs· batch 1130L-DK
For
KPV
by CertaPeptides· batch CP-2607-KPV10
For
KPV
by Forge Performance Co.· batch KPV10-2609-01-BLU-SLV
For
KPV
by Peptide Plugs· batch 71110L-DK
For
KPV
by Rescue Research USA· batch RR-KPV-2609
For
KPV
by Velora Biolabs· batch VBL-KPV10-1
For
KPV
by Synthesis Peptides· batch KPV10926
For
KPV
by Sunrise Bioresearch· batch KPVJUN26-01
For
KPV
by Sunrise Bioresearch· batch KPVJUN26-01
For
KPV
by VoriLabs· batch VoriLabs KPV-2607-A
For
KPV
by jdbioworks· batch 2026-002
For
KPV
by Artisan Aminos· batch AA-KPV10-049
For
KPV
by NG Peptide· batch KP10-06
For
KPV
by Peptide Plugs· batch 101-05-ZB
For
KPV
by Ignite Peptides· batch KPV1012321
For
KPV
by OROS Research· batch OR-LPKPV15-626-B3
For
KPV
by Optima Supply· batch OS-2026-1179
For
KPV
by Hydro Research Peptides· batch HR-2026-4981
For
KPV
by optimasupply.is· batch OS-2026-1179
For
KPV
by Apexx Biolabs· batch Purple Cap-1
For
KPV
by Mile High Compounds· batch KPV-010-MH-05
For
KPV
by Soma Peptides· batch KPX062609
For
KPV
by Peptide Partners· batch SPL-4157
For
KPV
by Peptide Partners· batch KV202606
12 citations indexed for KPV
Study · 2026
Lysine-Proline-Valine attenuates oxidized low-density lipoprotein-induced foam cell formation and inflammatory responses in RAW264.7 macrophages
Atherosclerosis develops through oxidative stress and inflammatory responses induced by oxidized low-density lipoprotein (oxLDL), and excessive lipid accumulation in macrophages accelerates disease progression by facilitating foam cell formation.
animal · 2026
KPV attenuates adipogenesis and lipid metabolism through modulation of ROS-mediated AKT/mTORC1/PPARγ signaling
Lysine-Proline-Valine (KPV), an endogenous tripeptide derived from α-melanocyte-stimulating hormone, has been recognized for its anti-inflammatory and antioxidant activities. However, its role in adipocyte differentiation has not been investigated.
Study · 2026
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells
Hepatocellular steatosis, an early stage within the non-alcoholic fatty liver disease (NAFLD) spectrum, is characterized by excessive lipid accumulation and oxidative stress in hepatocytes.
Study · 2026
Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers
Oral delivery of peptide therapeutics remains challenging due to gastrointestinal (GI) degradation and poor intestinal absorption.
in-vitro · 2026
Exploration of 1,3,4-Thiadiazole Bearing Quinolin-2(1H)-One Hybrids as Potent Antimycobacterial Agents: Design, Synthesis, and In Silico Docking Techniques
Introduction The development of novel quinolin-2(1H)-one-fused 1,3,4-thiadiazole heterocyclic hybrids was achieved through structural optimization as potential antimicrobial/anti- TB agents.
review · 2026
Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards
Compounded peptides have quickly moved from a niche topic to a growing area of interest among patients and prescribers. These products are promoted for a wide range of uses, including tissue repair, inflammation, metabolic health, and healthy aging.