For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Healing & Recovery

KPV

Also known as: Lysine-Proline-Valine (alpha-MSH 11-13)

KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH), corresponding to residues 11-13. It is the smallest alpha-MSH fragment shown to retain anti-inflammatory activity. Research-only; not FDA-approved; evidence is primarily preclinical.

Where to buy · live market data

Who's worth your money for KPV

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

Highest Merit Score (99) of 33 scored sellers

$5.20/mg

$51.99 · 10mg · 99.2% purity

3 COAs
Buy code MERIT · 10% off

Best value after code

$0.05/mg effective with 15% code

$0.06/mg

$0.55 · 10mg · 98.2% purity

2 COAs
Buy code MERIT · 15% off

Most tested

15 independent COAs on file

$3.30/mg

$33.00 · 10mg · 99.6% purity

Average price

$5.55/mg

Sellers

77

45-day trend

-10.3%

64 of 77 sellers have a current price· 21 stale hidden· 10 unverified hidden

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

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Compound reference

About KPV

CAS

67727-97-3

Molecular formula

C16H30N4O4

Sequence

KPV

Typical dose range

250–500 mcg/day subcutaneous (research use)

Half-life

~4–6 hours (rodent pharmacokinetic data; human data lacking)

Independent evidence

COAs for KPV

158 third-party tests across 40 vendors. Each card links to the full report.

All 158 COAs for KPV →
Measured purity 97.8%–100.0% across 109 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.41 %
Aug 2026
ILS Labs Strong

For

KPV

by Sunrise Bioresearch· batch KPVJUN26-01

✓ Vendor-published
99.41 %
Aug 2026
ILS Laboratories

For

KPV

by Sunrise Bioresearch· batch KPVJUN26-01

COA on file
Aggregated · 3rd-party listing
99.66 %
Jul 2026
ILS Labs Strong

For

KPV

by NG Peptide· batch KP10-06

Aggregated · 3rd-party listing
99.49 %
Jul 2026
Freedom Diagnostics Moderate

For

KPV

by Peptide Plugs· batch 101-05-ZB

Aggregated · 3rd-party listing
99.00 %
Jul 2026
ILS Labs Strong

For

KPV

by Ignite Peptides· batch KPV1012321

Aggregated · 3rd-party listing
99.00 %
Jun 2026
Ethos Analytics Strong

For

KPV

by OROS Research· batch OR-LPKPV15-626-B3

Aggregated · 3rd-party listing
98.16 %
Jun 2026
Janoshik Analytical Limited

For

KPV

by Optima Supply· batch OS-2026-1179

Aggregated · 3rd-party listing
98.16 %
Jun 2026
Janoshik Analytical Limited

For

KPV

by Hydro Research Peptides· batch HR-2026-4981

✓ Vendor-published
98.16 %
Jun 2026
Janoshik Analytical Limited

For

KPV

by optimasupply.is· batch OS-2026-1179

COA on file
Aggregated · 3rd-party listing
99.60 %
Jun 2026
Freedom Diagnostics Moderate

For

KPV

by Apexx Biolabs· batch Purple Cap-1

Aggregated · 3rd-party listing
99.71 %
Jun 2026
ILS Labs Strong

For

KPV

by Mile High Compounds· batch KPV-010-MH-05

Aggregated · 3rd-party listing
98.49 %
Jun 2026
Prime Analytical Laboratories, LLC

For

KPV

by Soma Peptides· batch KPX062609

✓ Vendor-published
99.39 %
Jun 2026
TrustPointe Analytics Moderate

For

KPV

by Peptide Partners· batch SPL-4157

COA on file
✓ Vendor-published
99.70 %
Jun 2026
Kovera Labs

For

KPV

by Peptide Partners· batch KV202606

COA on file
Aggregated · 3rd-party listing
99.37 %
Jun 2026
Freedom Diagnostics Moderate

For

KPV

by Peptide Supply Co.· batch KPV10 06032026

Aggregated · 3rd-party listing
99.19 %
Jun 2026
ILS Labs Strong

For

KPV

by Crush Research· batch CR-KPV-10-2605-1

Aggregated · 3rd-party listing
99.80 %
May 2026
Vanguard Laboratory Strong

For

KPV

by Moglabs· batch KPV002

Aggregated · 3rd-party listing
99.18 %
May 2026
Janoshik Analytical Limited

For

KPV

by EZ Peptides· batch EZP-KPV1005152026-12

✓ Vendor-published
99.18 %
May 2026
Janoshik Analytical Limited

For

KPV

by EZ Peptides· batch EZP-KPV1005152026-12

COA on file
Aggregated · 3rd-party listing
99.64 %
May 2026
Freedom Diagnostics Moderate

For

KPV

by True Peptide· batch KPV1-019-TPL

Aggregated · 3rd-party listing
99.87 %
May 2026
Freedom Diagnostics Moderate

For

KPV

by Modern Research Peptides· batch BCRTHK23461

Aggregated · 3rd-party listing
99.33 %
May 2026
Freedom Diagnostics Moderate

For

KPV

by Nox Amino· batch NA-KP0526-01

Aggregated · 3rd-party listing
99.28 %
May 2026
Horizon Analytical

For

KPV

by Blank Peptides· batch BP-4451178-P

Aggregated · 3rd-party listing
99.72 %
May 2026
ILS Labs Strong

For

KPV

by NG Peptide· batch KP10-05

Research depth

12 citations indexed for KPV

All research on KPV →

animal · 2026

KPV attenuates adipogenesis and lipid metabolism through modulation of ROS-mediated AKT/mTORC1/PPARγ signaling

Lysine-Proline-Valine (KPV), an endogenous tripeptide derived from α-melanocyte-stimulating hormone, has been recognized for its anti-inflammatory and antioxidant activities. However, its role in adipocyte differentiation has not been investigated.

Study · 2026

Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells

Hepatocellular steatosis, an early stage within the non-alcoholic fatty liver disease (NAFLD) spectrum, is characterized by excessive lipid accumulation and oxidative stress in hepatocytes.

review · 2026

Influence of Water Source Quality on Concrete Performance: A Mechanism-Based Systematic Review and Engineering Evaluation Framework

The use of alternative water sources in concrete production has gained increasing attention due to growing concerns over water scarcity and sustainability; however, existing studies predominantly evaluate water suitability based on compressive strength, often overlooking durability performance and underlying material b…

in-vitro · 2026

Exploration of 1,3,4-Thiadiazole Bearing Quinolin-2(1H)-One Hybrids as Potent Antimycobacterial Agents: Design, Synthesis, and In Silico Docking Techniques

Introduction The development of novel quinolin-2(1H)-one-fused 1,3,4-thiadiazole heterocyclic hybrids was achieved through structural optimization as potential antimicrobial/anti- TB agents.

Study · 2026

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers

Oral delivery of peptide therapeutics remains challenging due to gastrointestinal (GI) degradation and poor intestinal absorption.

Study · 2026

Subspecies Identification and Characterization of Drug Resistance and Virulence Factors in Clinical Strains of <i>Mycobacterium abscessus</i> Complex Isolated from South India

Background Mycobacterium abscessus complex (MABC), comprising Mycobacterium abscessus subsp. abscessus (MABa), Mycobacterium abscessus subsp. bolletii (MABb), and Mycobacterium abscessus subsp.