Melanotan II
Also known as: MT-2
Melanotan II (MT-II) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) — Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 — developed at the University of Arizona in the 1980s by Hruby, Hadley, and colleagues as a candidate photoprotection / sunless-tanning agent. It has never been approved by the FDA or any other regulator for any indication; clinical development was abandoned and it is sold only via grey-market research-chemical channels. Genuine safety signals have been reported, including darkening of existing moles, eruptive atypical nevi, and case reports of new primary melanoma in young tanning-seeking users.
Pricing for Melanotan II
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
COAs for Melanotan II
38 third-party tests across 17 vendors. Each card links to the full report.
For
Melanotan II
by Crush Research· batch CR-MT2-10-2605-1
For
Melanotan II
by Verified Peptides· batch MT206260510E
For
Melanotan II
by Skye Peptides· batch MT226-10-001
For
Melanotan II
by Prime Peptides· batch 3092026MT2
For
Melanotan II
by Prime Peptides· batch 3132026MT2
For
Melanotan II
by Moglabs· batch MT202
For
Melanotan II
by Peptide Plugs· batch 120-A-S
For
Melanotan-2
by OROS Research· batch OR-LPMT2-426-B5
For
Melanotan-2
by Glacier Aminos· batch MT210GA-03
For
Melanotan II
by Blank Peptides· batch 665394
For
Melanotan-2
by Crush Research· batch CR-MT210-2603-1
For
Melanotan II
by Forge Performance Co.· batch Black Cap
For
Melanotan 2
by Peptide Supply Co.· batch MT21003232026
For
Melanotan-2
by Mile High Compounds· batch MLN-010-MH-01
For
Melanotan-2
by Glacier Aminos· batch MT210GA-02
For
Melanotan 2
by Peptide Supply Co.· batch cmpa6pnc1000r73rxbarj9ys4
For
Melanotan II
by NG Peptide· batch MT01
For
Melanotan 2
by Skye Peptides· batch MT225-10-004
For
Melanotan II
by Hydro Research Peptides· batch HYDRO11WN68L
For
Melanotan II
by Ion Peptide· batch MTII-1025
For
Melanotan II
by Simple Peptide· batch MEL209032025-J
For
Melanotan 2
by Orbitrex Peptides· batch TAN123
For
Melanotan II
by Profound Aminos· batch 2025-04-03
For
Melanotan II
by Simple Peptide· batch MEL21011072025-04
16 citations indexed for Melanotan II
case-report · 2026
Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report
This case report presents a three-month follow-up of a patient who self-administered Melanotan II injections over a period of 64 days with the goal of achieving a deeper tanning effect. Melanotan II is an unlicensed synthetic peptide analog belonging to the melanocortin hormone family.
review · 2026
Insights into Tanning Biology and Tanning Products
Objective This systematic review aims to critically assess the literature on the mechanisms of action, clinical uses, formulation strategies, and adverse effects of self-tanning agents, with a focus on dihydroxyacetone (DHA), melanotan, forskolin, and carotenoids.
rct · 2026
Melanotan II (MT-II) as an Adjunct to NB-UVB Phototherapy for Repigmentation in Stable Nonsegmental Vitiligo
This example interventional study record describes a randomized Phase 2 clinical trial evaluating investigational Melanotan II (MT-II) as an adjunct to standard NB-UVB phototherapy for repigmentation in adults with stable nonsegmental vitiligo.
review · 2026
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Therapeutic peptides are short chains of amino acids used to treat metabolic and endocrine conditions such as obesity and type 2 diabetes.
review · 2026
Targeting Peptidergic Systems for Melanoma Treatment
Melanoma is a heterogeneous, complex and aggressive disease that, despite recent advances in molecular-targeted drugs and molecular and genetic analysis, represents approximately 65% of skin cancer deaths, and unfortunately survival dramatically decreases in melanoma stages III/IV.
Study · 2026
The tectal melanocortin system modulates energy-dependent visual avoidance behavior in zebrafish
Energy homeostasis depends on both food intake and behavioral control of energy expenditure. The hypothalamic melanocortin system is classically associated with feeding regulation, but its broader behavioral roles remain less defined.