MGF
Also known as: Mechano Growth Factor, IGF-1Ec, IGF-1 Ec
Mechano Growth Factor is the C-terminal E-domain peptide derived from IGF-1Ec, a splice variant of insulin-like growth factor 1 that is expressed locally and transiently in skeletal muscle in response to mechanical loading or damage. After cleavage from the IGF-1 precursor, the 24-amino-acid MGF E-peptide acts independently of the IGF-1 receptor, helping activate quiescent satellite (muscle stem) cells to support muscle repair and hypertrophy. Synthetic MGF is the unmodified peptide and is degraded rapidly in body fluids; the related PEG-MGF kept in this directory is the pegylated form, in which polyethylene glycol (and typically a stabilizing D-amino-acid substitution) is attached to extend half-life. MGF is not FDA-approved and is a grey-market research compound with no controlled human efficacy data.
Who's worth your money for MGF
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (85) of 1 scored sellers
$39.00 · 2mg · 99.3% purity
Average price
$14.86/mg
Sellers
7
45-day trend
-11.6%
7 of 7 sellers have a current price· 6 unverified hidden
- 🇺🇸 Simple Peptide85
✓ verified at source · just now
$19.50/mg +31.3% vs avg$39.00
2mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About MGF
CAS
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Molecular formula
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Sequence
YQPPSTNKNTKSQRRKGSTFEERK
Typical dose range
Vendor-reported research use commonly 100-200 mcg per injection, local/subcutaneous; no validated human dosing
Half-life
Very short (minutes-scale) for unmodified MGF due to rapid degradation in plasma; the pegylated PEG-MGF variant is engineered for a substantially longer half-life
Common research uses
Safety notes
Not FDA-approved for human use; sold as a research chemical only with no controlled human safety data. As an IGF-1-related growth factor it is prohibited at all times under the WADA Code (S2). Theoretical risks include effects on cell proliferation; purity and identity of grey-market product are unverified.
Reconstitution
Supplied as lyophilized powder; reconstitute with bacteriostatic water and refrigerate after reconstitution.
COAs for MGF
6 third-party tests across 3 vendors. Each card links to the full report.
For
MGF IGF-1
by Ruo Bio· batch MGF002
For
MGF
by Ruo Bio
For
MGF
by Ion Peptide· batch PMGF-121325
For
MGF
by Simple Peptide· batch MGF08252025-J
For
MGF
by Simple Peptide· batch MGF02072025-J
Purity not on file
For
MGF IGF-1
by Ruo Bio
20 citations indexed for MGF
Study · 2026
Spontaneous self-assembly of mangiferin in an aqueous medium into vesicles for anticancer drug encapsulation and antibacterial applications
Natural products exhibiting spontaneous vesicular self-assembly are rare. Mangiferin, a natural xanthonoid, was isolated from the rhizome of the fern Davallia solida . Herein, we demonstrate that mangiferin spontaneously self-assembles in aqueous and organic-aqueous binary solutions, forming stable spherical vesicles.
review · 2026
Mangiferin as a Multilevel Modulator of Metabolic Syndrome: Current Evidence and Future Perspectives
Background/Objectives : The obesogenic environment is a key factor in the rising prevalence of metabolic syndrome (MetS), a major global public health challenge. Mangiferin (Mgf) is a C-glycosylated xanthone, and its preventive and therapeutic potential stems from its multisystemic pharmacological profile.
animal · 2026
Comprehensive molecular profiling of the African swine fever virus in Korean wild boars between 2019 and 2024
African swine fever (ASF), caused by the African swine fever virus (ASFV), is a lethal transboundary disease. Since its first detection in South Korea in 2019, ASFV has continuously infected wild boars, imposing major economic and ecological burdens.
Study · 2026
Lignin-based macromolecular composite solid electrolyte enabling high-performance sodium metal batteries via MgF<sub>2</sub>-assisted ion dissociation
Solid polymer electrolytes (SPEs) for sodium metal batteries often suffer from low room-temperature ionic conductivity and unstable electrode/electrolyte interfaces.
Study · 2026
Pathways of fluoride removal and MgF<sub>2</sub> recovery from fluoride-containing wastewater using different magnesium sources
Removing fluoride from fluoride-containing wastewater while recovering fluorine resources is important for both environmental protection and resource utilization.
Study · 2026
Antibacterial performance of chitosan-modified magnesium fluoride nanoparticles: Synthesis and characterization
The rise of multidrug-resistant bacterial infections threatens human health by reducing the effectiveness of conventional antibiotics. This growing challenge highlights the urgent need for advanced nano-based antibacterial materials capable of overcoming resistance and providing broad-spectrum protection.
Research use only — not for human consumption and not approved by the FDA. Nothing here is medical advice.