MGF
Also known as: Mechano Growth Factor, IGF-1Ec, IGF-1 Ec
Mechano Growth Factor is the C-terminal E-domain peptide derived from IGF-1Ec, a splice variant of insulin-like growth factor 1 that is expressed locally and transiently in skeletal muscle in response to mechanical loading or damage. After cleavage from the IGF-1 precursor, the 24-amino-acid MGF E-peptide acts independently of the IGF-1 receptor, helping activate quiescent satellite (muscle stem) cells to support muscle repair and hypertrophy. Synthetic MGF is the unmodified peptide and is degraded rapidly in body fluids; the related PEG-MGF kept in this directory is the pegylated form, in which polyethylene glycol (and typically a stabilizing D-amino-acid substitution) is attached to extend half-life. MGF is not FDA-approved and is a grey-market research compound with no controlled human efficacy data.
Who's worth your money for MGF
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (84) of 2 scored sellers
$66.00 · 5mg
Best value
Lowest $/mg among scored sellers
$29.99 · 2mg
Average price
$15.83/mg
Sellers
8
45-day trend
-7%
6 of 8 sellers have a current price· 1 stale hidden· 3 unverified hidden
Top Merit pick
🇺🇸 Alpha Omega84✓ verified at source · 8h ago
$13.20/mg -16.6% vs avg$66.00
5mg
no purity- 🇺🇸 AMC Essentials30
✓ verified at source · 8h ago
$14.99/mg -5.3% vs avg$29.99
2mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About MGF
CAS
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Molecular formula
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Sequence
YQPPSTNKNTKSQRRKGSTFEERK
Typical dose range
Vendor-reported research use commonly 100-200 mcg per injection, local/subcutaneous; no validated human dosing
Half-life
Very short (minutes-scale) for unmodified MGF due to rapid degradation in plasma; the pegylated PEG-MGF variant is engineered for a substantially longer half-life
Common research uses
Safety notes
Not FDA-approved for human use; sold as a research chemical only with no controlled human safety data. As an IGF-1-related growth factor it is prohibited at all times under the WADA Code (S2). Theoretical risks include effects on cell proliferation; purity and identity of grey-market product are unverified.
Reconstitution
Supplied as lyophilized powder; reconstitute with bacteriostatic water and refrigerate after reconstitution.
COAs for MGF
6 third-party tests across 3 vendors. Each card links to the full report.
For
MGF IGF-1
by Ruo Bio· batch MGF002
For
MGF
by Ruo Bio
For
MGF
by Ion Peptide· batch PMGF-121325
For
MGF
by Simple Peptide· batch MGF08252025-J
For
MGF
by Simple Peptide· batch MGF02072025-J
Purity not on file
For
MGF IGF-1
by Ruo Bio
20 citations indexed for MGF
Study
Multimodal graph-based fusion via image descriptions for few-shot open-set recognition
Few-shot open-set recognition (FSOR) presents unique challenges due to the limited labeled samples and the presence of unknown classes during inference.
Study · 2026
RIXS reveals sub-20-femtosecond lattice relaxation around two core excitons in MgO and MgF<sub>2</sub>
Soft X-ray emission at the Mg L 2,3 edge of MgO and MgF 2 reveals weak continuous energy-loss tails (ELTs) adjacent to the elastic scattering lines. These ELTs are attributed to lattice relaxation around core excitons.
Study · 2026
Montage-guided fusion network for long-term scalp electroencephalography seizure detection
Introduction Automatic seizure detection from long-term scalp electroencephalography (EEG) can reduce the burden of manual EEG review. However, multi-derivation EEG is commonly processed as a collection of input channels without explicitly modeling the structured relations defined by the bipolar montage.
Study · 2026
Mutilations génitales féminines et excision
Study · 2026
Novel cardiac computed tomography-based preoperative indicator associated with intraoperative graft flow in coronary artery bypass grafting
Study · 2026
Sustainable Extraction of Mangiferin From Mango Leaves Using Taguchi and Box-Behnken Optimization: Biochemical Characterization and Antioxidant Profiling
Mangiferin (MGF), a bioactive C-glucosylxanthone predominantly found in Mangifera indica L., has attracted increasing interest due to its recognized antioxidant and pharmacological properties.
Research use only. Not for human consumption and not approved by the FDA.