MOTS-c
Also known as: Mitochondrial Open reading frame of the Twelve S rRNA type-c
MOTS-c is an investigational mitochondrial-derived peptide studied preclinically for metabolic regulation. It is research-only and not FDA-approved; the CB4211 analog program (CohBar) was discontinued in 2023.
Pricing for MOTS-c
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
Average price
$5.08/mg
range $0.00–$45.00/mg
Sellers
91
from $0.00
45-day trend
-3%
vs 45-day avg $/mg
78 of 91 sellers have a current price· 19 stale listings hidden (not seen in 7 days)
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · 4h ago
$2.30/mg -54.7% vs avg$45.99
20mg
- 🇺🇸 Peptide Partners99
✓ verified at source · 3h ago
$6.30/mg +24.1% vs avg$252
40mg
- 🇺🇸 BioLongevity Labs96
✓ verified at source · 3h ago
$11.00/mg +116.7% vs avg$110
10mg
- 🇺🇸 Reta One Labs95
✓ verified at source · 3h ago
$1.80/mg -64.5% vs avg$72.00
40mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 4h ago
$3.50/mg -31% vs avg$140
40mg
99.0% purity 5 COAs - 🇺🇸 Prime Peptides95
via Disclosed Labs · 4h ago
$5.50/mg +8.4% vs avg$55.00
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 3h ago
$45.00/mg +786.6% vs avg$450
10mg
- 🇺🇸 Mile High Compounds94
✓ verified at source · 4h ago
$1.25/mg -75.4% vs avg$49.99
40mg
99.7% purity 2 COAs - 🇺🇸 Forge Performance Co.94
✓ verified at source · 3h ago
$3.00/mg -40.9% vs avg$60.00
20mg
- 🇺🇸 Hydro Research Peptides91
✓ verified at source · 3h ago
$3.50/mg -31% vs avg$35.00
10mg
- 🇺🇸 Ignite Peptides91
✓ verified at source · 4h ago
$4.80/mg -5.4% vs avg$48.00
10mg
no purity - 🇺🇸 Peptidology89
✓ verified at source · 4h ago
$1.23/mg -75.9% vs avg$49.00
40mg
- 🇺🇸 Peptide Plugs89
✓ verified at source · 4h ago
$2.50/mg -50.7% vs avg$100
40mg
- 🇺🇸 Arcane Peptides88
✓ verified at source · 4h ago
$5.00/mg -1.5% vs avg$50.00
10mg
no purity 1 COA - 🇺🇸 Verified Peptides86
via Disclosed Labs · 4h ago
$3.85/mg -24.1% vs avg$77.00
20mg
- 🇺🇸 Simple Peptide85
✓ verified at source · 3h ago
$4.30/mg -15.3% vs avg$43.00
10mg
- 🇺🇸 EZ Peptides85
✓ verified at source · 4h ago
$5.40/mg +6.4% vs avg$54.00
10mg
99.7% purity 4 COAs - Peptide Supply Co.83
via Disclosed Labs · 4h ago
$1.25/mg -75.4% vs avg$500
400mg
99.7% purity 6 COAs - 🇺🇸 Ascension Peptides83
via Disclosed Labs · 4h ago
$4.90/mg -3.5% vs avg$49.00
10mg
no purity - 🇨🇳 Reta Peptide83
✓ verified at source · 4d ago · stale
$6.50/mg +28.1% vs avg$65.00
10mg
99.4% purity 1 COA - 🇺🇸 MedGe Peptides82
✓ verified at source · 3h ago
$6.50/mg +28.1% vs avg$65.00
10mg
- 🇺🇸 Blank Peptides81
✓ verified at source · 4h ago
$5.50/mg +8.4% vs avg$55.00
10mg
99.5% purity 2 COAs - 🇺🇸 OROS Research79
via Disclosed Labs · 4h ago
$5.00/mg -1.5% vs avg$99.99
20mg
99.0% purity 3 COAs - 🇺🇸 Texpeptide70
✓ verified at source · 3h ago
$4.50/mg -11.3% vs avg$45.00
10mg
no purity - 🇨🇳 Qing Li Peptide63
✓ verified at source · 4h ago
$0.00/mg -100% vs avg$0.00
10mg
99.8% purity 1 COA - 🇺🇸 Certified Peptides61
✓ verified at source · 4h ago
$5.80/mg +14.3% vs avg$58.00
10mg
no purity 3 COAs - Sports Technology Labs59
✓ verified at source · 4h ago
$11.40/mg +124.6% vs avg$56.99
5mg
no purity - 🇺🇸 Puratek Peptides44
✓ verified at source · 4h ago
$0.75/mg -85.2% vs avg$29.95
40mg
no purity - 🇭🇰 zztai Peptide Ltd43
✓ verified at source · 4d ago · stale
$5.00/mg -1.5% vs avg$200
40mg
no purity - Nextech Labs24
✓ verified at source · 4h ago
$10.00/mg +97% vs avg$99.99
10mg
no purity - 🇺🇸 Southern AminosUnscored
✓ verified at source · 4h ago
$0.77/mg -84.8% vs avg$30.80
40mg
no purity - True PeptideUnscored
✓ verified at source · 4h ago
$0.90/mg -82.3% vs avg$36.00
40mg
no purity - 🇺🇸 Oasis LabsUnscored
✓ verified at source · 4h ago
$1.21/mg -76.1% vs avg$48.50
40mg
no purity - Nova PeptidesUnscored
✓ verified at source · 4h ago
$1.25/mg -75.4% vs avg$49.99
40mg
no purity - synthesispeptides.ioUnscored
✓ verified at source · 4h ago
$1.25/mg -75.4% vs avg$49.99
40mg
no purity - Amino SequenceUnscored
✓ verified at source · 4h ago
$1.75/mg -65.5% vs avg$70.00
40mg
no purity - 🇺🇸 Genetic PeptideUnscored
✓ verified at source · 4h ago
$1.83/mg -63.9% vs avg$110
60mg
no purity - 🇺🇸 NG PeptideUnscored
via Disclosed Labs · 4h ago
$2.00/mg -60.6% vs avg$80.00
40mg
no purity - 🇺🇸 AMC EssentialsUnscored
✓ verified at source · 4h ago
$2.25/mg -55.7% vs avg$89.99
40mg
no purity - S1 ResearchUnscored
✓ verified at source · 4h ago
$2.40/mg -52.7% vs avg$24.00
10mg
no purity - volterasciences.comUnscored
via Disclosed Labs · 4h ago
$2.50/mg -50.7% vs avg$99.99
40mg
no purity - 🇺🇸 Alpha PeptidesUnscored
via Disclosed Labs · 4h ago
$2.75/mg -45.7% vs avg$27.55
10mg
no purity - 🇺🇸 Oneday CompoundsUnscored
✓ verified at source · 4h ago
$3.25/mg -36% vs avg$32.49
10mg
no purity - 🇺🇸 Peptide CraftersUnscored
✓ verified at source · 4h ago
$3.67/mg -27.8% vs avg$55.00
15mg
no purity - peptidetech.isUnscored
via Disclosed Labs · 4h ago
$4.50/mg -11.4% vs avg$44.99
10mg
no purity - 🇺🇸 Atomik LabzUnscored
✓ verified at source · 4h ago
$4.50/mg -11.3% vs avg$45.00
10mg
no purity - Solution PeptidesUnscored
✓ verified at source · 4h ago
$4.50/mg -11.3% vs avg$45.00
10mg
no purity - 🇺🇸 PeptiraUnscored
✓ verified at source · 4h ago
$4.90/mg -3.5% vs avg$49.00
10mg
no purity - 🇺🇸 Pepvida LabsUnscored
✓ verified at source · 4h ago
$4.90/mg -3.5% vs avg$49.00
10mg
no purity - 🇺🇸 Kimera ChemsUnscored
via Disclosed Labs · 4h ago
$5.00/mg -1.5% vs avg$49.99
10mg
no purity - 🇺🇸 Polaris PeptidesUnscored
✓ verified at source · 4h ago
$5.50/mg +8.4% vs avg$55.00
10mg
no purity - 🇺🇸 Paramount PeptidesUnscored
✓ verified at source · 4h ago
$5.53/mg +8.9% vs avg$55.25
10mg
no purity - 🇺🇸 Felix Chemical SupplyUnscored
✓ verified at source · 4h ago
$6.00/mg +18.2% vs avg$59.99
10mg
no purity - optimasupply.isUnscored
via Disclosed Labs · 4h ago
$6.50/mg +28.1% vs avg$65.00
10mg
no purity - realpeptides.coUnscored
via Disclosed Labs · 4h ago
$7.00/mg +37.9% vs avg$280
40mg
no purity - 🇺🇸 Soma PeptidesUnscored
✓ verified at source · 4h ago
$7.90/mg +55.7% vs avg$79.00
10mg
no purity - 🇺🇸 Biotech PeptidesUnscored
✓ verified at source · 4h ago
$9.90/mg +95.1% vs avg$99.00
10mg
no purity - 🇺🇸 Core PeptidesUnscored
✓ verified at source · 4h ago
$11.60/mg +128.6% vs avg$116
10mg
no purity - 🇺🇸 Bulk PeptidesUnscored
✓ verified at source · 4h ago
$18.00/mg +254.7% vs avg$180
10mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
COAs for MOTS-c
277 third-party tests across 40 vendors. Each card links to the full report.
For
MOTS-C
by Peptide Plugs· batch 149-01-DK
For
MOTS-c
by Ruo Bio· batch MOT002
For
MOTS-c
by Moglabs· batch MOT002
For
MOTS-c
by Ruo Bio· batch MOT402
For
MOTS-C
by NG Peptide· batch MS40-08
For
MOTS-c
by Real Peptides· batch RP062326MC
For
MOTS-C
by Sunrise Bioresearch· batch MTC10MAY26-02
For
MOTS-C
by Sunrise Bioresearch· batch MTC10MAY26-02
For
MOTS-C
by Apexx Biolabs· batch Light Purple Cap-1
For
MOTS-c
by Real Peptides· batch BATCH-0322
For
MOTS-C
by Ion Peptide· batch MC40-06032026
For
MOTS-C
by Ion Peptide· batch MCD4-06022026
For
MOTS-C
by Peptide Plugs· batch 127-02-DK
For
MOTS-C
by Peptide Partners· batch SPL-4096
For
MOTS-C
by Voltera Sciences· batch MS40.05.28.26
For
MOTS-C
by Verified Peptides· batch M005261320L
For
MOTS-C
by Crush Research· batch CRMTS-40-2605-2
For
MOTS-C
by Crush Research· batch CR-MOTS20-2605-1
For
MOTS-C
by Crush Research· batch CRMTS-40-2605-1
For
MOTS-C
by Crush Research· batch CRMTS-10-2605-1
For
MOTS-c
by Reta One Labs· batch MTS100626
For
MOTS-C
by Nox Amino· batch NA-MS0226-01
For
MOTS-c
by Blank Peptides· batch B-7058391-P
For
MOTS-C
by NG Peptide· batch MTS40-07
23 citations indexed for MOTS-c
cohort · 2027
Mitophagy and Mitochondrial DNA Dynamics During Ramadan Dry Fasting vs 16:8 Time-Restricted Feeding
This study investigates how different types of fasting affect cell health, specifically focusing on how mitochondria (the energy-producing parts of cells) are cleared and renewed.
Study · 2026
Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?
Objective MOTS-c is a mitochondria-derived peptide associated with reduced insulin resistance and obesity. The m.1382A>C polymorphism of the MOTS-c gene is linked to an increased risk of type 2 diabetes in men.
animal · 2026
MOTS-c partially protects against skeletal muscle deterioration in C26 cachexia
Background Cancer cachexia is a multifactorial metabolic syndrome marked by progressive skeletal muscle loss, reduced function, and increased mortality. Mitochondrial dysfunction is a key driver of this phenotype.
Study · 2026
Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction
Background: Atrial fibrillation (AF) is a common clinical arrhythmia associated with mitochondrial dysfunction, oxidative stress, and atrial fibrosis. Mitochondrial-derived peptides (MDPs), including humanin (HN) and MOTS-c, exhibit cytoprotective properties, but their role in AF remains largely unknown.
Study · 2026
Mitochondrial peptide MOTS-c suppresses systemic and cardiac inflammasome activation in a diabetic rat model
Type 2 diabetes mellitus (T2DM) is associated with chronic systemic and cardiac inflammation, contributing to the development of diabetic cardiomyopathy.
review · 2026
MOTS-c: How a secreted mitochondrial microprotein may become a potential treatment for inflammatory lung diseases
Background MOTS-c is a mitochondrial-derived microprotein (mitokine) encoded within the 12 S rRNA gene that exerts intracrine, paracrine, and endocrine effects across multiple tissues.