SS-31
Also known as: Elamipretide
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) developed by Hazel Szeto (Cornell) and clinically advanced by Stealth BioTherapeutics. It concentrates in the inner mitochondrial membrane by binding cardiolipin. In September 2025, the FDA granted accelerated approval to elamipretide (brand name FORZINITY) as the first therapy for Barth syndrome — the first FDA-approved mitochondria-targeted drug. It remains investigational for other indications.
Pricing for SS-31
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
Average price
$4.68/mg
range $0.00–$20.00/mg
Sellers
59
from $0.00
45-day trend
+5.5%
vs 45-day avg $/mg
51 of 59 sellers have a current price· 22 stale listings hidden (not seen in 7 days)
Top Merit pick
🇺🇸 Peptide Partners99✓ verified at source · 3h ago
$6.40/mg +36.7% vs avg$320
50mg
- 🇺🇸 Reta One Labs95
✓ verified at source · 4h ago
$3.40/mg -27.4% vs avg$34.00
10mg
99.2% purity 2 COAs - 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 4h ago
$5.40/mg +15.3% vs avg$270
50mg
99.8% purity 4 COAs - 🇺🇸 Hydro Research Peptides91
via Disclosed Labs · 4h ago
$3.50/mg -25.2% vs avg$175
50mg
99.9% purity 3 COAs - 🇺🇸 Peptide Plugs89
✓ verified at source · 4h ago
$2.60/mg -44.5% vs avg$130
50mg
- Peptide Supply Co.83
via Disclosed Labs · 4h ago
$1.25/mg -73.3% vs avg$625
500mg
- 🇺🇸 Ascension Peptides83
via Disclosed Labs · 4h ago
$6.00/mg +28.2% vs avg$60.00
10mg
- 🇺🇸 OROS Research79
via Disclosed Labs · 4h ago
$3.67/mg -21.7% vs avg$110
30mg
99.0% purity 2 COAs - 🇺🇸 Texpeptide70
✓ verified at source · 3h ago
$5.50/mg +17.5% vs avg$55.00
10mg
no purity - 🇨🇳 Qing Li Peptide63
✓ verified at source · 4h ago
$0.00/mg -100% vs avg$0.00
10mg
no purity - 🇭🇰 zztai Peptide Ltd43
✓ verified at source · 4d ago · stale
$8.34/mg +78.1% vs avg$417
50mg
no purity - Nextech Labs24
✓ verified at source · 4h ago
$2.30/mg -50.9% vs avg$115
50mg
no purity - True PeptideUnscored
✓ verified at source · 4h ago
$1.00/mg -78.6% vs avg$50.00
50mg
no purity - Wellness PeptidesUnscored
✓ verified at source · 4h ago
$1.10/mg -76.5% vs avg$55.00
50mg
no purity - 🇺🇸 Genetic PeptideUnscored
✓ verified at source · 4h ago
$1.20/mg -74.4% vs avg$60.00
50mg
no purity - 🇺🇸 Soma PeptidesUnscored
✓ verified at source · 4h ago
$2.36/mg -49.6% vs avg$59.00
25mg
no purity - 🇺🇸 Peptide CraftersUnscored
✓ verified at source · 4h ago
$2.44/mg -48% vs avg$95.00
39mg
no purity - idunpeptides.comUnscored
via Disclosed Labs · 4h ago
$2.50/mg -46.6% vs avg$250
100mg
no purity - Platinum LionUnscored
✓ verified at source · 4h ago
$2.80/mg -40.2% vs avg$140
50mg
no purity - 🇺🇸 Pepvida LabsUnscored
✓ verified at source · 4h ago
$3.18/mg -32.1% vs avg$159
50mg
no purity - optimasupply.isUnscored
via Disclosed Labs · 4h ago
$3.50/mg -25.2% vs avg$175
50mg
no purity - 🇺🇸 Alpha PeptidesUnscored
via Disclosed Labs · 4h ago
$3.58/mg -23.6% vs avg$35.79
10mg
no purity - 🇺🇸 Atomik LabzUnscored
✓ verified at source · 4h ago
$3.98/mg -15% vs avg$199
50mg
no purity - Solution PeptidesUnscored
✓ verified at source · 4h ago
$3.98/mg -15% vs avg$199
50mg
no purity - 🇺🇸 PeptiraUnscored
✓ verified at source · 4h ago
$4.90/mg +4.7% vs avg$49.00
10mg
no purity - 🇺🇸 Polaris PeptidesUnscored
✓ verified at source · 4h ago
$5.16/mg +10.2% vs avg$129
25mg
no purity - realpeptides.coUnscored
via Disclosed Labs · 4h ago
$5.40/mg +15.3% vs avg$270
50mg
no purity - 🇺🇸 Apollo Peptide SciencesUnscored
✓ verified at source · 4h ago
$10.00/mg +113.6% vs avg$99.99
10mg
no purity - 🇺🇸 Bulk PeptidesUnscored
✓ verified at source · 4h ago
$20.00/mg +327.2% vs avg$200
10mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
COAs for SS-31
117 third-party tests across 21 vendors. Each card links to the full report.
For
SS-31
by Ion Peptide· batch 2510-06242026
For
SS-31
by Ion Peptide· batch 2S10-06242026
For
SS-31
by Reta One Labs· batch SS100626
For
S-31
by Ion Peptide· batch SS3150-05042026
For
S-31
by Ion Peptide· batch SS3150-05042026
For
SS-31
by Ion Peptide· batch 2S10-05042026
For
S-31
by Ion Peptide· batch 2S10-05042026
For
SS-31
by Peptidegurus· batch cmojgr89m002r9grxu1x2sttx
For
SS-31
by Peptide Plugs· batch 121-A-D
For
SS-31
by Peptide Partners· batch SPL-3436
For
§-31
by Ion Peptide· batch §-3110-03242026
For
§-31
by Ion Peptide· batch §-3150-03232026
For
SS-31
by Forge Performance Co.· batch Blue Top
For
SS-31
by Qihang Peptide· batch 3
For
SS-31
by Glacier Aminos· batch MTP10GA-03
For
SS-31
by Mile High Compounds· batch SS3-010-MH-04
For
SS-31
by Ion Peptide· batch C3150-02272026
For
SS-31
by Orbitrex Peptides· batch MTP100326
For
SS-31
by Qihang Peptide· batch 2
For
SS-31
by Peptide Supply Co.· batch PSCSS3150001
For
SS-31
by Peptide Partners· batch SS202602
For
SS-31
by Peptide Partners· batch SS202602
For
SS-31
by Ion Peptide· batch SS3110-02032026
For
SS-31
by Licensed Peptides· batch LP02202016
14 citations indexed for SS-31
Study · 2026
Mitochondrial-targeted SS-31 peptide attenuates radiation-induced cardiomyocyte senescence
Exposure to ionizing radiation, such as from radiation therapy or accidental radiation exposure can have adverse effects on the heart. While radiation injury in the heart may include cardiomyocyte senescence, there are no available strategies to prevent this phenomenon.
in-vitro · 2026
Mitochondrial-Targeted SS-31 Attenuates the Doxorubicin-Induced Cardiomyoblast H9C2 Cell Senescence
Doxorubicin (DOX), an effective chemotherapeutic agent for many types of cancer, is known for significant cardiotoxic side effects, which largely limit its clinical usage.
animal · 2026
Targeting Mitochondrial Dysfunction With Elamipretide (SS-31) Improves Skeletal Muscle Performance in a HFpEF Rat Model
Background Exercise intolerance, promoted by skeletal muscle- and mitochondrial dysfunction, has been identified as a therapeutic target in heart failure with preserved ejection fraction (HFpEF).
Study · 2026
Therapeutic Peptide SS-31 Modulates Membrane Binding and Aggregation of α-Synuclein and Restores Impaired Mitochondrial Function
Membrane binding and aggregation properties of α-synuclein are closely associated with Parkinson's disease and a class of related syndromes named as synucleinopathy.
animal · 2026
Elamipretide (SS-31) and Nicotinamide Mononucleotide (NMN) Combination Therapy Targets TREM2 to Mitigate Post-ischemic Brain Injury in Mice
Ischemic stroke is a severe cerebrovascular disorder characterized by a cascade of pathological processes, including neuroinflammation and apoptosis. These processes lead to high mortality rates and long-term disabilities, imposing substantial socioeconomic burdens.
animal · 2026
Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury
Spinal cord injury (SCI) induces secondary damage characterized by mitochondrial dysfunction, oxidative stress, and apoptosis, which collectively impede neurological recovery. Elamipretide (SS-31) is a mitochondria-targeting peptide with potential neuroprotective effects.