Thymosin Alpha-1
Also known as: Thymalfasin (trade name Zadaxin)
Thymosin Alpha-1 (Ta1) is a 28-amino-acid thymic peptide (Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN) approved as Zadaxin in 35+ countries for chronic hepatitis B/C and as an immune adjuvant. It is NOT FDA-approved in the US.
Who's worth your money for Thymosin Alpha-1
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 40 scored sellers
$370 · 100mg · 100.0% purity
Best value
Lowest $/mg among scored sellers
$32.00 · 10mg
Most tested
23 independent COAs on file
$80.00 · 10mg · 99.6% purity
Average price
$8.78/mg
Sellers
66
45-day trend
-15.4%
51 of 66 sellers have a current price· 1 stale hidden· 10 unverified hidden
Top Merit pick
🇺🇸 Peptide Partners99via Disclosed Labs · 1h ago
$3.70/mg -57.9% vs avg$370
100mg
- 🇺🇸 Glacier Aminos99
✓ verified at source · 1h ago
$4.48/mg -49% vs avg$44.79
10mg
- 🇺🇸 Moglabs98
✓ verified at source · 1h ago
$7.20/mg -18% vs avg$36.00
5mg
no purity - 🇺🇸 Hydro Research Peptides97
via Disclosed Labs · 1h ago
$6.50/mg -26% vs avg$65.00
10mg
- 🇺🇸 BioLongevity Labs96
via Disclosed Labs · 1h ago
$13.00/mg +48% vs avg$130
10mg
- 🇺🇸 Reta One Labs95
via Disclosed Labs · 1h ago
$3.20/mg -63.6% vs avg$32.00
10mg
- 🇺🇸 Profound Aminos95
via Disclosed Labs · 1h ago
$6.50/mg -26% vs avg$65.00
10mg
- 🇺🇸 Orbitrex Peptides95
via Disclosed Labs · 1h ago
$7.00/mg -20.3% vs avg$69.99
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · 1h ago
$12.40/mg +41.2% vs avg$61.99
5mg
- 🇺🇸 Sunrise Bioresearch95
✓ verified at source · 1h ago
$40.00/mg +355.5% vs avg$200
5mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Thymosin Alpha-1
CAS
62304-98-7
Molecular formula
C129H215N33O55
Sequence
SDAAVDTSSEITTKDLKEKKEVVEEAEN
Typical dose range
1.6 mg subcutaneous 2–3x/week (clinical standard); research protocols range 1.6–6.4 mg per dose
Half-life
~2–3 hours (subcutaneous; elimination t½ <3 h confirmed by PK study)
COAs for Thymosin Alpha-1
138 third-party tests across 33 vendors. Each card links to the full report.
For
Thymosin Alpha-1
by Novaglo Research· batch 3001092826TA
For
Thymosin Alpha-1
by Hydro Research Peptides· batch HR-2026-1289
For
Thymosin Alpha-1
by VoriLabs· batch TA1-K2609-A
For
Thymosin Alpha-1
by Peptuvia· batch PSTA110-2
For
Thymosin Alpha-1
by Velora Biolabs· batch VBL-TA10-1
For
Thymosin Alpha-1
by Synthesis Peptides· batch TA110926
For
Thymosin Alpha-1
by CertaPeptides· batch CP-2607-THA5
For
Thymosin Alpha-1
by CertaPeptides· batch CP-2604-TA10
For
Thymosin Alpha-1
by Blank Peptides· batch DPS-8269267
For
Thymosin Alpha-1
by NG Peptide· batch TA1-05
For
Thymosin Alpha-1
by OROS Research· batch OR-LPTA5-626-B2
For
Thymosin Alpha-1
by EZ Peptides· batch EZP-TA11006052026-04
For
Thymosin Alpha-1
by Modern Research Peptides· batch 982444TU
For
Thymosin Alpha-1
by Verified Peptides· batch TA05260910H
For
Thymosin Alpha-1
by Blank Peptides· batch THYMA10-052026-7
For
Thymosin Alpha-1
by Soma Peptides· batch TAXV042603
For
Thymosin Alpha-1
by Skye Peptides· batch TA126-10-001
For
Thymosin Alpha-1
by Real Peptides· batch Black Cap
For
Thymosin Alpha-1
by Pepsgpt· batch P-1947064-P
For
Thymosin Alpha-1
by Riptide Wellness· batch RWTA1-10-1003
For
Thymosin alpha-1
by Ion Peptide· batch TA110-04202026
For
Thymosin Alpha-1
by Peptide Supply Co.· batch TA1004132026
For
Thymosin Alpha-1
by OROS Research· batch OR-LPTA5-326-B1
For
Thymosin
by Verified Peptides· batch cmojb57q300trkirxximley58
20 citations indexed for Thymosin Alpha-1
Study · 2026
Thymosin Alpha-1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis
Communication between the immune system and the brain is critical for neuronal health, yet the molecular signals that mediate this crosstalk are not fully understood. Here, we uncover an unexpected and direct neuroprotective axis linking the thymus to the central nervous system (CNS).
review · 2026
Clinical Applications and Evidence Landscape of Thymosin Alpha 1 as an Immunomodulatory Adjunct in Cancer Care: A Scoping Review
Background : Thymosin alpha 1 (Tα1, thymalfasin) is a thymus-derived immunomodulatory peptide investigated as an adjunctive therapy in cancer care. Although studied across malignancies, its evidence landscape has not been systematically mapped.
Study · 2026
Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells
Chemotherapy induces cancer cell apoptosis and the release of apoptotic bodies (AB) that are poorly immunogenic or immunosuppressive, creating a major barrier to the success of coadministered or second-line immunotherapies.
Study · 2026
A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1
To report a case of a nasopharyngeal carcinoma patient who developed multisystem immune-related adverse events (irAEs) after treatment with sintilimab (PD-1 inhibitor) in combination with thymosin alpha-1 (Tα1). The patient presents with high fever, rash, interstitial pulmonary edema, and multiple organ failure.
rct · 2026
Study of Adebrelimab Combined With Thymalfasin and Chemotherapy for Neoadjuvant Treatment of Esophageal Cancer
This is a prospective, single-arm, multicenter clinical study conducted in China.
review · 2025
Aging and Thymosin Alpha-1
Aging is characterized by immune decline, mainly due to thymic involution-the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases.