Thymosin Alpha-1
Also known as: Thymalfasin (trade name Zadaxin)
Thymosin Alpha-1 (Ta1) is a 28-amino-acid thymic peptide (Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN) approved as Zadaxin in 35+ countries for chronic hepatitis B/C and as an immune adjuvant. It is NOT FDA-approved in the US.
Who's worth your money for Thymosin Alpha-1
Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.
Top Merit pick
Highest Merit Score (99) of 31 scored sellers
$63.99 · 10mg · 99.7% purity
Best value after code
$0.06/mg effective with 15% code
$0.65 · 10mg · 99.2% purity
Most tested
21 independent COAs on file
$48.00 · 10mg · 99.6% purity
Average price
$8.83/mg
Sellers
71
45-day trend
-10.7%
59 of 71 sellers have a current price· 20 stale hidden· 8 unverified hidden
Top Merit pick
🇺🇸 Glacier Aminos99✓ verified at source · just now
$6.40/mg -27.6% vs avg$63.99
10mg
- 🇺🇸 Hydro Research Peptides97
✓ verified at source · just now
$0.07/mg -99.3% vs avg$0.65
10mg
- 🇺🇸 Moglabs96
✓ verified at source · just now
$7.20/mg -18.5% vs avg$36.00
5mg
no purity - 🇺🇸 BioLongevity Labs96
✓ verified at source · just now
$13.00/mg +47.1% vs avg$130
10mg
- 🇺🇸 Licensed Peptides95
✓ verified at source · just now
$12.40/mg +40.3% vs avg$61.99
5mg
- 🇺🇸 Peptide Crafters94
✓ verified at source · just now
$5.53/mg -37.5% vs avg$55.25
10mg
- 🇺🇸 Forge Performance Co.94
✓ verified at source · just now
$6.00/mg -32.1% vs avg$60.00
10mg
no purityBuy code MERIT · 10% off - 🇺🇸 Riptide Wellness92
✓ verified at source · just now
$6.50/mg -26.4% vs avg$65.00
10mg
- 🇺🇸 Polaris Peptides90
✓ verified at source · just now
$6.50/mg -26.4% vs avg$65.00
10mg
no purity - 🇺🇸 Peptidology89
✓ verified at source · just now
$1.03/mg -88.3% vs avg$69.99
68mg
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
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About Thymosin Alpha-1
CAS
62304-98-7
Molecular formula
C129H215N33O55
Sequence
SDAAVDTSSEITTKDLKEKKEVVEEAEN
Typical dose range
1.6 mg subcutaneous 2–3x/week (clinical standard); research protocols range 1.6–6.4 mg per dose
Half-life
~2–3 hours (subcutaneous; elimination t½ <3 h confirmed by PK study)
COAs for Thymosin Alpha-1
124 third-party tests across 33 vendors. Each card links to the full report.
For
Thymosin Alpha-1
by Blank Peptides· batch DPS-8269267
For
Thymosin Alpha-1
by NG Peptide· batch TA1-05
For
Thymosin Alpha-1
by OROS Research· batch OR-LPTA5-626-B2
For
Thymosin Alpha-1
by EZ Peptides· batch EZP-TA11006052026-04
For
Thymosin Alpha-1
by Modern Research Peptides· batch 982444TU
For
Thymosin Alpha-1
by Verified Peptides· batch TA05260910H
For
Thymosin Alpha-1
by Blank Peptides· batch THYMA10-052026-7
For
Thymosin Alpha-1
by Soma Peptides· batch TAXV042603
For
Thymosin Alpha-1
by Skye Peptides· batch TA126-10-001
For
Thymosin Alpha-1
by Real Peptides· batch Black Cap
For
Thymosin Alpha-1
by Pepsgpt· batch P-1947064-P
For
Thymosin Alpha-1
by Riptide Wellness· batch RWTA1-10-1003
For
Thymosin alpha-1
by Ion Peptide· batch TA110-04202026
For
Thymosin Alpha-1
by Peptide Supply Co.· batch TA1004132026
For
Thymosin Alpha-1
by OROS Research· batch OR-LPTA5-326-B1
For
Thymosin
by Verified Peptides· batch cmojb57q300trkirxximley58
For
Thymosin Alpha-1
by Amino Club· batch THA0001
For
Thymosin alpha-1
by Ion Peptide· batch TA110-03232026
For
Thymosin alpha-1
by Ion Peptide· batch TA110-03232026
For
Thymosin Alpha-1
by Modern Research Peptides· batch MKUST5WC3526
For
Thymosin Alpha-1
by Profound Aminos· batch cmojb89io01hzkirx1zv5axqw
For
Thymosin Alpha-1
by Verified Peptides· batch TA032608106
For
Thymosin Alpha-1
by Peptide Partners· batch TA202602
For
Thymosin alpha-1
by Peptide Partners· batch TA202602
20 citations indexed for Thymosin Alpha-1
Study · 2026
Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells
Chemotherapy induces cancer cell apoptosis and the release of apoptotic bodies (ABs) that are poorly immunogenic or immunosuppressive, creating a major barrier to the success of co-administered or second-line immunotherapies.
Study · 2026
A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1
To report a case of a nasopharyngeal carcinoma patient who developed multisystem immune-related adverse events (irAEs) after treatment with sintilimab (PD-1 inhibitor) in combination with thymosin alpha-1 (Tα1). The patient presents with high fever, rash, interstitial pulmonary edema, and multiple organ failure.
rct · 2026
A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer
This study will enroll patients with locally advanced non-small cell lung cancer (NSCLC).
review · 2025
Aging and Thymosin Alpha-1
Aging is characterized by immune decline, mainly due to thymic involution-the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases.
Study · 2025
The Immunomodulatory Activity of Thymosin Alpha 1 on Tumor Cell Lines and Distinct Immune Cell Subsets
Background The immune-balancing role of thymosin alpha 1 (Tα1) is well-recognized in contexts of immune dysregulation. Within the anti-tumor context, Tα1 demonstrated to act as an immune-enhancer, with potential roles in immunotherapy-based treatments.
meta-analysis · 2025
Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis
Background Immune and inflammatory disorders are part of the complex pathophysiological processes that exacerbate severe acute pancreatitis (SAP) and subsequent infection.