For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

GLP-1 / Metabolic

Tirzepatide

Also known as: Tirzepatide (GIP/GLP-1 dual receptor agonist — Mounjaro, Zepbound)

Tirzepatide is a unimolecular dual GIP and GLP-1 receptor agonist with a half-life of approximately 5 days, enabling once-weekly subcutaneous dosing. It is FDA-approved as Mounjaro for type 2 diabetes (2022), Zepbound for chronic weight management in adults with obesity or overweight with a weight-related comorbidity (2023), and Zepbound for moderate-to-severe obstructive sleep apnea in adults with obesity (2024). It carries a BOXED WARNING for thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Where to buy · live market data

Who's worth your money for Tirzepatide

Every current seller, ranked by independent evidence — Merit Score, latest COA purity, and live $/mg (size-normalized). Prices refresh daily. Rankings are never paid.

Top Merit pick

Highest Merit Score (90) of 5 scored sellers

$11.00/mg

$55.00 · 5mg · 99.9% purity

Best value

Lowest $/mg among scored sellers

$0.50/mg

$10.00 · 20mg · 99.8% purity

Most tested

4 independent COAs on file

$2.97/mg

$89.00 · 30mg · 99.6% purity

Average price

$6.28/mg

Sellers

76

45-day trend

+21.7%

69 of 76 sellers have a current price· 64 stale hidden

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

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Compound reference

About Tirzepatide

CAS

2023788-19-2

Molecular formula

C225H348N48O68

Sequence

YXEGTFTSDYSIXLDKIAQKAFVQWLIAGGPSSGAPPPSamide

Typical dose range

2.5–15 mg once weekly subcutaneous injection (research studies mirror clinical titration: start 2.5 mg/week, escalate by 2.5 mg every 4 weeks to max 15 mg/week)

Half-life

~5 days (~120 hours)

Independent evidence

COAs for Tirzepatide

449 third-party tests across 55 vendors. Each card links to the full report.

All 449 COAs for Tirzepatide →
Measured purity 82.3%–100.0% across 289 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.88 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by Crush Research· batch CR-2XAG-60-2607-Purple

✓ Vendor-published
99.59 %
Jul 2026
Kovera Labs

For

Tirzeptide

by Ignite Peptides· batch IP-2607-127

COA on file
✓ Vendor-published
99.51 %
Jul 2026
Kovera Labs

For

Tirzepatide

by Ignite Peptides· batch IP-2607-797

COA on file
Aggregated · 3rd-party listing
100.00 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ40-15

Aggregated · 3rd-party listing
99.98 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by Hydro Research Peptides· batch HR-2026-3814

Aggregated · 3rd-party listing
99.91 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ20-14

Aggregated · 3rd-party listing
99.91 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ20-14

Aggregated · 3rd-party listing
99.22 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by Aspire Peptides· batch TR10-032026-1

Aggregated · 3rd-party listing
99.81 %
Jul 2026
ILS Labs Strong

For

Tirzepatide

by Aspire Peptides· batch TR15-032026-1

Aggregated · 3rd-party listing
99.94 %
Jun 2026
Accumark Labs

For

Tirzepatide

by Polaris Peptides· batch POL-T10-19

Aggregated · 3rd-party listing
99.68 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by Orbitrex Peptides· batch 2G30726

Aggregated · 3rd-party listing
99.95 %
Jun 2026
Freedom Diagnostics Moderate

For

Tirzepatide

by Ion Peptide· batch ION2T20-06242026

Aggregated · 3rd-party listing
99.89 %
Jun 2026
Freedom Diagnostics Moderate

For

Tirzepatide

by Profound Aminos· batch Clear Cap/Bronze Crimp

Aggregated · 3rd-party listing
99.58 %
Jun 2026
Freedom Diagnostics Moderate

For

Tirzepatide

by Blank Peptides· batch GT10-062026-6

Aggregated · 3rd-party listing
99.90 %
Jun 2026
Prime Analytical Laboratories, LLC

For

Tirzepatide

by Soma Peptides· batch TIXH0062661

✓ Vendor-published
99.11 %
Jun 2026
TrustPointe Analytics Moderate

For

Tirzepatide

by Peptide Partners· batch SPL-4130

COA on file
Aggregated · 3rd-party listing
99.88 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ30-13

Aggregated · 3rd-party listing
99.88 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ30-13

Aggregated · 3rd-party listing
99.82 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by Peptide Plugs· batch 005-B-SM

Aggregated · 3rd-party listing
99.90 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by NG Peptide· batch TRZ60-04

Aggregated · 3rd-party listing
99.03 %
Jun 2026
ILS Labs Strong

For

Tirzepatide

by Voltera Sciences· batch TR60.05.28.26

Aggregated · 3rd-party listing
100.00 %
Jun 2026
Prime Analytical Laboratories, LLC

For

Tirzepatide

by Soma Peptides· batch TILX052678

Aggregated · 3rd-party listing
99.95 %
Jun 2026
Freedom Diagnostics Moderate

For

Tirzepatide

by Blank Peptides· batch GT30-A5-062026-4

Aggregated · 3rd-party listing
99.77 %
Jun 2026
Janoshik Analytical Limited

For

Tirzepatide

by EZ Peptides· batch EZP-2P2005162026-04

Research depth

23 citations indexed for Tirzepatide

All research on Tirzepatide →

Study · 2026

Trends in Cost of Care With Tirzepatide in Adults Aged Over 55 Years With Obesity or Overweight Without Diabetes: A Matched Cohort Analysis

Aims Compare healthcare cost trends among older adults with obesity or overweight treated with tirzepatide versus no treatment. Materials and methods Retrospective cohort study using real-world data from US Komodo Research Dataset, 8 November 2022 to 30 September 2025.

rct · 2026

Liver Fat Changes in Patients With Type 2 Diabetes by Presence of Genetic Hepatic Steatosis: A Post Hoc Analysis of SURPASS-3 MRI

The patatin-like phospholipase 3 (PNPLA3) I148M genetic variant is highly associated with steatotic liver disease.

rct · 2026

Achieving the triple endpoint of body weight reduction thresholds, systolic blood pressure reduction ≥5 mmHg and non-HDL cholesterol <130 mg/dL with tirzepatide in people with obesity: A post hoc analysis from the SURMOUNT trials

Background Modest body weight reduction can greatly improve many health-related outcomes. In the SURMOUNT clinical trial program, once-weekly tirzepatide resulted in substantial body weight reductions in people with obesity, without and with type 2 diabetes.

Study · 2026

Tirzepatide Persistence and Associated Changes in Clinical Outcomes in US Adults With Obesity or Overweight: A 6-Month Claims Database Analysis

Aims Tirzepatide is a once-weekly glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist (GLP-1 RA) approved in the US for the treatment of Type 2 diabetes (T2D), weight loss and obstructive sleep apnoea.

review · 2026

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Background Heart failure with preserved ejection fraction (HFpEF) accounts for over half of all heart failure hospitalizations, with obesity increasingly recognized as a central driver through expansion of epicardial adipose tissue, chronic low-grade inflammation and obesity-related haemodynamic overload culminating in…

Study · 2026

Predicted 10-Year Cardiovascular Disease Risk Reduction with Tirzepatide Use Over Three Years for Primary Prevention of Cardiovascular Disease in Obesity

Aim This post hoc analysis assessed the durability of tirzepatide for primary cardiovascular disease (CVD) prevention in obesity, based on predicted CVD risk, in the SURMOUNT-1 (SM-1) 3-year study.